Kryptonite

Kyrptonite is superman's weakness it is very known among comics and movies, It is also used against superman in the old movies. It is from Krypton, in fact it is radioactive rocks and debree from krypton. He immediately feels dizzy, and disorientated when he is exposed to this substance. He loses hes super strength and if he is exposed to it for an extended period, he loses consciousness.